Nicholas P. Marotta

O-GlcNAc modification blocks the aggregation and toxicity of the protein α-synuclein associated with Parkinson's disease

Nicholas P. Marotta, Yu Lin, Yuka E. Lewis et al. · Nature Chemistry · 2015 · 300 citations · Full text

Neurodegenerative Diseases, O-glcnac Modification, Biochemistry +5

Semisynthetic, Site-Specific Ubiquitin Modification of α-Synuclein Reveals Differential Effects on Aggregation

Franziska Meier, Tharindumala Abeywardana, Abhinav Dhall et al. · Journal of the American Chemical Society · 2012 · 111 citations · Full text

Protein Assembly, Molecular Biology, Peptide Science +18

Alpha-synuclein from patient Lewy bodies exhibits distinct pathological activity that can be propagated in vitro

Nicholas P. Marotta, Jahan Ara, Norihito Uemura et al. · Acta Neuropathologica Communications · 2021 · 79 citations · Full text

The New Chemical Reporter 6-Alkynyl-6-deoxy-GlcNAc Reveals O-GlcNAc Modification of the Apoptotic Caspases That Can Block the Cleavage/Activation of Caspase-8

Kelly N. Chuh, Anna R. Batt, Balyn W. Zaro et al. · Journal of the American Chemical Society · 2017 · 62 citations · Full text

Bioorganic Chemistry, Apoptosis, Glycobiology +17

O‐GlcNAc Modification Prevents Peptide‐Dependent Acceleration of α‐Synuclein Aggregation

Nicholas P. Marotta, Carli A. Cherwien, Tharindumala Abeywardana et al. · ChemBioChem · 2012 · 60 citations