Concepedia
Statistics
Publications
19
Citations
1.8K
H-Index
17
Active since
2007
Affiliations
Peter MacCallum Cancer Centre(Current)
Monash University
The University of Melbourne
The University of Queensland
University of North Carolina at Chapel Hill
Keefe T. Chan is an author at Peter MacCallum Cancer Centre specializing in cell biology, medicine, and cell signaling.
Top concepts
MedicineCell BiologyCell SignalingTumor BiologyCell PhysiologySignal TransductionCancer BiologyCancer ResearchNatural SciencesCellular Biochemistry
Publications per year
2007–2023
FAK alters invadopodia and focal adhesion composition and dynamics to regulate breast cancer invasion
Keefe T. Chan, Christa L. Cortesio, Anna Huttenlocher · The Journal of Cell Biology · 2009 · 260 citations · Full text
Breast Oncology, Cell Adhesion, Cytoskeleton +22
CX-5461 activates the DNA damage response and demonstrates therapeutic efficacy in high-grade serous ovarian cancer
Elaine Sanij, Katherine M. Hannan, Jiachen Xuan et al. · Nature Communications · 2020 · 213 citations · Full text
Regulation of Adhesion Dynamics by Calpain-mediated Proteolysis of Focal Adhesion Kinase (FAK)
Keefe T. Chan, David A. Bennin, Anna Huttenlocher · Journal of Biological Chemistry · 2010 · 202 citations · Full text
Signal Transduction, Developmental Biology, Biochemistry +15
Calpain 2 and PTP1B function in a novel pathway with Src to regulate invadopodia dynamics and breast cancer cell invasion
Christa L. Cortesio, Keefe T. Chan, Benjamin J. Perrin et al. · The Journal of Cell Biology · 2008 · 182 citations · Full text
Cell Adhesion, Novel Pathway, Calpain 2 +22
LKB1/STK11 Inactivation Leads to Expansion of a Prometastatic Tumor Subpopulation in Melanoma
Wenjin Liu, Kimberly B. Monahan, Adam D. Pfefferle et al. · Cancer Cell · 2012 · 124 citations · Full text
Tumor Biology, Lkb1/stk11 Inactivation Leads, Medicine +10
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