Concepedia

Keefe T. Chan

KT

19

Publications

1.8K

Citations

17

H-Index

2007

Active since

Affiliations

Peter MacCallum Cancer Centre(Current)

Monash University

The University of Melbourne

The University of Queensland

University of North Carolina at Chapel Hill

Keefe T. Chan is an author at Peter MacCallum Cancer Centre specializing in cell biology, medicine, and cell signaling.

ORCID

Top concepts

Publications per year

2007–2023

19

Publications

19

FAK alters invadopodia and focal adhesion composition and dynamics to regulate breast cancer invasion

Keefe T. Chan, Christa L. Cortesio, Anna Huttenlocher · The Journal of Cell Biology · 2009 · 260 citations · Full text

, , +22

CX-5461 activates the DNA damage response and demonstrates therapeutic efficacy in high-grade serous ovarian cancer

Elaine Sanij, Katherine M. Hannan, Jiachen Xuan et al. · Nature Communications · 2020 · 213 citations · Full text

Regulation of Adhesion Dynamics by Calpain-mediated Proteolysis of Focal Adhesion Kinase (FAK)

Keefe T. Chan, David A. Bennin, Anna Huttenlocher · Journal of Biological Chemistry · 2010 · 202 citations · Full text

, , +15

Calpain 2 and PTP1B function in a novel pathway with Src to regulate invadopodia dynamics and breast cancer cell invasion

Christa L. Cortesio, Keefe T. Chan, Benjamin J. Perrin et al. · The Journal of Cell Biology · 2008 · 182 citations · Full text

, , +22

LKB1/STK11 Inactivation Leads to Expansion of a Prometastatic Tumor Subpopulation in Melanoma

Wenjin Liu, Kimberly B. Monahan, Adam D. Pfefferle et al. · Cancer Cell · 2012 · 124 citations · Full text

, , +10

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