Hugues Bernard

Probing the roles of SUMOylation in cancer cell biology by using a selective SAE inhibitor

Xingyue He, Jessica Riceberg, Teresa A. Soucy et al. · Nature Chemical Biology · 2017 · 223 citations

Selective Sae Inhibitor, Oncogenic Agent, Medicine +10

Mutation of NRAS but not KRAS significantly reduces myeloma sensitivity to single-agent bortezomib therapy

George Mulligan, David I. Lichter, Alessandra Di Bacco et al. · Blood · 2013 · 115 citations · Full text

Novel DNA Damage Checkpoints Mediating Cell Death Induced by the NEDD8-Activating Enzyme Inhibitor MLN4924

Jonathan L. Blank, Xiaozhen J. Liu, Katherine Cosmopoulos et al. · Cancer Research · 2012 · 101 citations · Full text

Apoptosis, Molecular Biology, Cell Death +16

Selective irreversible inhibition of a protease by targeting a noncatalytic cysteine

Margit Hagel, Deqiang Niu, Thia St Martin et al. · Nature Chemical Biology · 2010 · 92 citations

Selective Irreversible Inhibition, Biochemistry, Protein Folding +8

The beagle dog MicroRNA tissue atlas: identifying translatable biomarkers of organ toxicity

Erik Koenig, Craig D. Fisher, Hugues Bernard et al. · BMC Genomics · 2016 · 70 citations · Full text