Thomas H. Keller

Spiroindolones, a Potent Compound Class for the Treatment of Malaria

Matthias Rottmann, Case W. McNamara, Bryan K. S. Yeung et al. · Science · 2010 · 1.2K citations · Full text

Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Science +15

PA-824 Kills Nonreplicating <i>Mycobacterium tuberculosis</i> by Intracellular NO Release

Ramandeep Singh, Ujjini H. Manjunatha, Helena I. Boshoff et al. · Science · 2008 · 626 citations · Full text

Bioorganic Chemistry, Nitric Oxide, Tuberculosis Prevention +19

Structural basis for the activation of flaviviral NS3 proteases from dengue and West Nile virus

P. Erbel, Nikolaus Schiering, A. D’Arcy et al. · Nature Structural & Molecular Biology · 2006 · 567 citations

Virus Structure, Viral Replication, Pathogenesis +10

Spirotetrahydro β-Carbolines (Spiroindolones): A New Class of Potent and Orally Efficacious Compounds for the Treatment of Malaria

Bryan K. S. Yeung, Bin Zou, Matthias Rottmann et al. · Journal of Medicinal Chemistry · 2010 · 420 citations · Full text

An adenosine nucleoside inhibitor of dengue virus

Zheng Yin, Yen‐Liang Chen, Wouter Schul et al. · Proceedings of the National Academy of Sciences · 2009 · 389 citations · Full text

Dengue Virus, Molecular Virology, Medicine +9