Inhibition of CDK1 as a potential therapy for tumors over-expressing MYC

Andrei Goga, Dun Yang, Aaron D. Tward, +2

Nature Medicine

OncologyMedicineReceptor Tyrosine KinasePotential TherapyImmune Checkpoint Inhibitor +5

Short RNA duplexes produced by hydrolysis with <i>Escherichia coli</i> RNase III mediate effective RNA interference in mammalian cells

Dun Yang, Frank Buchholz, Zhongdong Huang, +4

Proceedings of the National Academy of Sciences

GeneticsRna SplicingMolecular BiologyTranscriptional RegulationLong Non-coding Rna +18

Evidence that processed small dsRNAs may mediate sequence-specific mRNA degradation during RNAi in Drosophila embryos

Dun Yang, Hong Lü, James Erickson

Current Biology

Small DsrnasTranscriptional RegulationDevelopmental BiologyGeneticsRna Biology +7

Cell division and cell survival in the absence of survivin

Dun Yang, Alana L. Welm, J. Michael Bishop

Proceedings of the National Academy of Sciences

ApoptosisCell DeathMolecular BiologyPathologyCell Proliferation +16

MYC suppresses cancer metastasis by direct transcriptional silencing of αv and β3 integrin subunits

Liu Hong, Derek C. Radisky, Dun Yang, +4

Nature Cell Biology

Tumor BiologyMedicineCancer Cell BiologyCell-matrix InteractionCancer Metastasis +6

Therapeutic potential of a synthetic lethal interaction between the <i>MYC</i> proto-oncogene and inhibition of aurora-B kinase

Dun Yang, Hong Liu, Andrei Goga, +3

Proceedings of the National Academy of Sciences

Therapeutic PotentialOverexpress MycSynthetic Lethal InteractionApoptosisImmunology +17

Tissue-specific RNA interference in postimplantation mouse embryos with endoribonuclease-prepared short interfering RNA

Federico Calegari, Wulf Haubensak, Dun Yang, +2

Proceedings of the National Academy of Sciences

The anti-apoptotic proteins Bcl-2 and Bcl-xL suppress Beclin 1/Atg6-mediated lethal autophagy in polyploid cells

Jing Zhang, Shenqiu Zhang, Qiong Shi, +3

Experimental Cell Research

Cell AutophagyMitophagyAutoimmune DiseaseApoptosisAutophagy +8

RNA Interference (RNAi) With RNase III-Prepared siRNAs

Dun Yang, Andrei Goga, J. Michael Bishop

Humana Press eBooks

Systems BiologyEngineeringRna InterferenceGeneticsActive Sirna +12

Double-layer fuzzy adaptive NMPC coordinated control method of energy management and trajectory tracking for hybrid electric fixed wing UAVs

Weiyong Tian, Li Liu, Xiaohui Zhang, +1

International Journal of Hydrogen Energy

EngineeringAerial RoboticsEnergy ManagementAerospace EngineeringAdaptive Control +6