Takayoshi Kinoshita

Identification of a selective ERK inhibitor and structural determination of the inhibitor–ERK2 complex

Makoto Ohori, Takayoshi Kinoshita, Mitsuru Okubo et al. · Biochemical and Biophysical Research Communications · 2005 · 223 citations

Molecular Pharmacology, Medicinal Chemistry, Structural Determination +10

Cell-based screen identifies a new potent and highly selective CK2 inhibitor for modulation of circadian rhythms and cancer cell growth

Tsuyoshi Oshima, Yoshimi Niwa, Keiko Kuwata et al. · Science Advances · 2019 · 128 citations · Full text

Molecular Regulation, Molecular Biology, Circadian Clock +22

Decay-accelerating factor is present on cultured human umbilical vein endothelial cells.

Adam S. Asch, Takayoshi Kinoshita, E A Jaffe et al. · The Journal of Experimental Medicine · 1986 · 126 citations · Full text

Endothelial Cells, Immunology, Blood Cell +23

Discovery of 6-Oxo-3-(2-phenylpyrazolo[1,5-<i>a</i>]pyridin-3-yl)-1(6<i>H</i>)-pyridazinebutanoic Acid (FK 838):  A Novel Non-Xanthine Adenosine A₁Receptor Antagonist with Potent Diuretic Activity

Atsushi Akahane, Hirohito Katayama, Takafumi Mitsunaga et al. · Journal of Medicinal Chemistry · 1999 · 102 citations · Full text

Rational Approaches to Discovery of Orally Active and Brain-Penetrable Quinazolinone Inhibitors of Poly(ADP-ribose)polymerase

Kouji Hattori, Yoshiyuki Kido, Hirofumi Yamamoto et al. · Journal of Medicinal Chemistry · 2004 · 95 citations · Full text

Drug Target, Bioorganic Chemistry, Orally Active +18