Chander Peddaboina

The novel BH3 α-helix mimetic JY-1-106 induces apoptosis in a subset of cancer cells (lung cancer, colon cancer and mesothelioma) by disrupting Bcl-xL and Mcl-1 protein–protein interactions with Bak

Xiaobo Cao, Jeremy L. Yap, M. Karen Newell‐Rogers et al. · Molecular Cancer · 2013 · 86 citations · Full text

The downregulation of Mcl-1 via USP9X inhibition sensitizes solid tumors to Bcl-xl inhibition

Chander Peddaboina, Daniel C. Jupiter, Steven Fletcher et al. · BMC Cancer · 2012 · 80 citations · Full text

Relaxation of the rigid backbone of an oligoamide-foldamer-based α-helix mimetic: identification of potent Bcl-xL inhibitors

Jeremy L. Yap, Xiaobo Cao, Kenno Vanommeslaeghe et al. · Organic & Biomolecular Chemistry · 2012 · 58 citations

Attenuation of Blood-Brain Barrier Breakdown and Hyperpermeability by Calpain Inhibition

Himakarnika Alluri, Marcene Grimsley, Chinchusha Anasooya Shaji et al. · Journal of Biological Chemistry · 2016 · 47 citations · Full text

Mast cells and histamine are triggering the NF-κB-mediated reactions of adult and aged perilymphatic mesenteric tissues to acute inflammation

Irina Tsoy Nizamutdinova, Giuseppina Dusio, Olga Yu. Gasheva et al. · Aging · 2016 · 44 citations · Full text