Helen M. Melo

An anti-diabetes agent protects the mouse brain from defective insulin signaling caused by Alzheimer’s disease–associated Aβ oligomers

Theresa R. Bomfim, Letícia Forny‐Germano, Luciana B. Sathler et al. · Journal of Clinical Investigation · 2012 · 812 citations · Full text

Synaptic Transmission, Synaptic Signaling, Insulin Signaling +28

Memantine Rescues Transient Cognitive Impairment Caused by High-Molecular-Weight A  Oligomers But Not the Persistent Impairment Induced by Low-Molecular-Weight Oligomers

Cláudia P. Figueiredo, Jason Clarke, José Henrique Ledo et al. · Journal of Neuroscience · 2013 · 184 citations · Full text

Neuropsychology, Persistent Impairment Induced, Synaptic Transmission +25

Astrocyte Transforming Growth Factor Beta 1 Protects Synapses against Aβ Oligomers in Alzheimer's Disease Model

Luan Pereira Diniz, Vanessa Tortelli, Isadora Matias et al. · Journal of Neuroscience · 2017 · 174 citations · Full text

Cross Talk Between Brain Innate Immunity and Serotonin Signaling Underlies Depressive-Like Behavior Induced by Alzheimer's Amyloid-β Oligomers in Mice

José Henrique Ledo, Estefania P. Azevedo, Danielle Beckman et al. · Journal of Neuroscience · 2016 · 134 citations · Full text

Palmitate Is Increased in the Cerebrospinal Fluid of Humans with Obesity and Induces Memory Impairment in Mice via Pro-inflammatory TNF-α

Helen M. Melo, Gisele da S. Seixas da Silva, Marcella Ramos Sant’Ana et al. · Cell Reports · 2020 · 125 citations · Full text