James R. Piper

Antibody-targeted liposomes: increase in specific toxicity of methotrexate-gamma-aspartate.

Timothy D. Heath, Jane Montgomery, James R. Piper et al. · Proceedings of the National Academy of Sciences · 1983 · 109 citations · Full text

Targeted Liposomes, Nanomedicine, Drug Targeting +11

Syntheses and antifolate activity of 5-methyl-5-deaza analogs of aminopterin, methotrexate, folic acid, and N10-methylfolic acid

James R. Piper, G. S. MCCALEB, Jane Montgomery et al. · Journal of Medicinal Chemistry · 1986 · 105 citations · Full text

A new analogue of 10-deazaaminopterin with markedly enhanced curative effects against human tumor xenografts in mice

Francis M. Sirotnak, Joseph I. DeGraw, William T. Colwell et al. · Cancer Chemotherapy and Pharmacology · 1998 · 87 citations

Curative Effects, Endocrine-related Cancer, Human Tumor Xenografts +9

Antimycobacterial Activities of 2,4-Diamino-5-Deazapteridine Derivatives and Effects on Mycobacterial Dihydrofolate Reductase

William J. Suling, Lainne E. Seitz, Vibha Pathak et al. · Antimicrobial Agents and Chemotherapy · 2000 · 73 citations · Full text

S-[2-(.omega.-Aminoalkylamino)ethyl] dihydrogen phosphorothioates and related compounds as potential antiradiation agents

James R. Piper, Carl R. Stringfellow, Robert D. Elliott et al. · Journal of Medicinal Chemistry · 1969 · 68 citations

Medicinal Chemistry, Bioorganic Chemistry, Donut Icon +14