Limeng Wu

Design, synthesis and biological evaluation of novel coumarin derivatives as multifunctional ligands for the treatment of Alzheimer's disease

Wenjie Liu, Limeng Wu, Wenwu Liu et al. · European Journal of Medicinal Chemistry · 2022 · 46 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +16

Discovery of novel β-carboline derivatives as selective AChE inhibitors with GSK-3β inhibitory property for the treatment of Alzheimer's disease

Wenwu Liu, Xin Liu, Wenjie Liu et al. · European Journal of Medicinal Chemistry · 2021 · 45 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +13

An inhibitor with GSK3β and DYRK1A dual inhibitory properties reduces Tau hyperphosphorylation and ameliorates disease in models of Alzheimer's disease

Xin Liu, Lingyun Lai, Jiang-xia Chen et al. · Neuropharmacology · 2023 · 28 citations

Life Sciences, Molecular Biology, Neuroscience +14

Discovery of novel β-carboline-1,2,3-triazole hybrids as AChE/GSK-3β dual inhibitors for Alzheimer's disease treatment

Wenjie Liu, Liting Tian, Limeng Wu et al. · Bioorganic Chemistry · 2022 · 27 citations

Pharmacy, Medicinal Chemistry, Pharmacology +9

Design, synthesis, and biological evaluation of β-carboline 1,3,4-oxadiazole based hybrids as HDAC inhibitors with potential antitumor effects

Caizhi Tian, Shuoqi Huang, Zihua Xu et al. · Bioorganic & Medicinal Chemistry Letters · 2022 · 22 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +12