Zihua Xu

Design, synthesis and biological evaluation of harmine derivatives as potent GSK-3β/DYRK1A dual inhibitors for the treatment of Alzheimer's disease

Wenwu Liu, Xin Liu, Liting Tian et al. · European Journal of Medicinal Chemistry · 2021 · 74 citations · Full text

Inhibitory Activity, Medicinal Chemistry, Derivatives +12

Arctium lappa L. roots ameliorates cerebral ischemia through inhibiting neuronal apoptosis and suppressing AMPK/mTOR-mediated autophagy

Yang Yue, Huan Gao, Wenwu Liu et al. · Phytomedicine · 2021 · 49 citations

Cerebral Ischemia, Mitophagy, Cell Autophagy +15

Design, synthesis and biological evaluation of novel coumarin derivatives as multifunctional ligands for the treatment of Alzheimer's disease

Wenjie Liu, Limeng Wu, Wenwu Liu et al. · European Journal of Medicinal Chemistry · 2022 · 43 citations · Full text

Combinatorial Chemistry, Medicinal Chemistry, Neurodegenerative Diseases +11

Discovery of novel β-carboline derivatives as selective AChE inhibitors with GSK-3β inhibitory property for the treatment of Alzheimer's disease

Wenwu Liu, Xin Liu, Wenjie Liu et al. · European Journal of Medicinal Chemistry · 2021 · 38 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Pharmaceutical Chemistry +13

Notopterygium incisum extract (NRE) rescues cognitive deficits in APP/PS1 Alzhneimer's disease mice by attenuating amyloid-beta, tau, and neuroinflammation pathology

Xiaowen Jiang, Wenwu Liu, Yuting Wu et al. · Journal of Ethnopharmacology · 2019 · 35 citations

Notopterygium Incisum Extract, Neurodegenerative Diseases, Alzheimer's Disease +13