Malcolm D. Walkinshaw

Insights into antifolate resistance from malarial DHFR-TS structures

Jirundon Yuvaniyama, P. Chitnumsub, Sumalee Kamchonwongpaisan et al. · Nature Structural & Molecular Biology · 2003 · 402 citations · Full text

Biochemistry, Antifolate Resistance, Medicine +5

Order-disorder transition for a bacterial polysaccharide in solution. A role for polysaccharide conformation in recognition between Xanthomonas pathogen and its plant host

E.R. Morris, David A. Rees, Graham A. Young et al. · Journal of Molecular Biology · 1977 · 381 citations

Polysaccharide Conformation, Bacterial Polysaccharide, Virulence Factor +8

MeCP2 Binding to DNA Depends upon Hydration at Methyl-CpG

Kok Lian Ho, I.W. McNae, Lars Schmiedeberg et al. · Molecular Cell · 2008 · 281 citations · Full text

Chromatin, Nucleic Acid Chemistry, Biochemistry +6

Structure of human cyclophilin and its binding site for cyclosporin A determined by X-ray crystallography and NMR spectroscopy

Jörg Kallen, Claus Spitzfaden, Mauro Zurini et al. · Nature · 1991 · 269 citations

Molecular Characterization, Nmr Spectroscopy, Biochemistry +11

Consensus Docking: Improving the Reliability of Docking in a Virtual Screening Context

Douglas R. Houston, Malcolm D. Walkinshaw · Journal of Chemical Information and Modeling · 2013 · 258 citations

Engineering, Machine Learning, Hit Identification +19