Claus Spitzfaden

Type IIA topoisomerase inhibition by a new class of antibacterial agents

B.D. Bax, Pan F. Chan, Drake S. Eggleston et al. · Nature · 2010 · 842 citations

Medicine, Medicinal Chemistry, Pharmacology +13

Structure of human cyclophilin and its binding site for cyclosporin A determined by X-ray crystallography and NMR spectroscopy

Jörg Kallen, Claus Spitzfaden, Mauro Zurini et al. · Nature · 1991 · 272 citations

Life Sciences, Biochemistry, Molecular Biology +5

Inhibition of fibril formation in beta-amyloid peptide by a novel series of benzofurans.

David Howlett, Amanda Perry, Fiona GODFREY et al. · PubMed · 1999 · 180 citations · Full text

Pharmacy, Biochemistry, Pharmacology +15

Structural basis of DNA gyrase inhibition by antibacterial QPT-1, anticancer drug etoposide and moxifloxacin

Pan F. Chan, Srikannathasan Velupillai, Jianzhong Huang et al. · Nature Communications · 2015 · 159 citations · Full text

Medicine, Pharmacology, Chemotherapy +14

Destabilization of the complete protein secondary structure on binding to the chaperone GroEL

Ralph Zahn, Claus Spitzfaden, Marcel Ottiger et al. · Nature · 1994 · 142 citations

Life Sciences, Biochemistry, Molecular Biology +14