P. Chitnumsub

Insights into antifolate resistance from malarial DHFR-TS structures

Jirundon Yuvaniyama, P. Chitnumsub, Sumalee Kamchonwongpaisan et al. · Nature Structural & Molecular Biology · 2003 · 411 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +14

Malarial dihydrofolate reductase as a paradigm for drug development against a resistance-compromised target

Yongyuth Yuthavong, Bongkoch Tarnchompoo, Tirayut Vilaivan et al. · Proceedings of the National Academy of Sciences · 2012 · 279 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Three-dimensional structure of M. tuberculosis dihydrofolate reductase reveals opportunities for the design of novel tuberculosis drugs

Rongbao Li, Rachada Sirawaraporn, P. Chitnumsub et al. · Journal of Molecular Biology · 2000 · 205 citations

Life Sciences, Biochemistry, Medicinal Chemistry +14

Mechanism-guided tunnel engineering to increase the efficiency of a flavin-dependent halogenase

Kridsadakorn Prakinee, Aisaraphon Phintha, Surawit Visitsatthawong et al. · Nature Catalysis · 2022 · 113 citations

Engineering, Chemical Engineering, Biocatalysis +7

Crystal structure of dihydrofolate reductase from <i>Plasmodium vivax</i> : Pyrimethamine displacement linked with mutation-induced resistance

Palangpon Kongsaeree, Ubolsree Leartsakulpanich, P. Chitnumsub et al. · Proceedings of the National Academy of Sciences · 2005 · 98 citations · Full text

Life Sciences, Biochemistry, Pharmacology +16