Rachada Sirawaraporn

Antifolate-resistant mutants of <i>Plasmodium falciparum</i> dihydrofolate reductase

Worachart Sirawaraporn, Tanajit Sathitkul, Rachada Sirawaraporn et al. · Proceedings of the National Academy of Sciences · 1997 · 342 citations · Full text

Life Sciences, Genetics, Molecular Biology +14

Three-dimensional structure of M. tuberculosis dihydrofolate reductase reveals opportunities for the design of novel tuberculosis drugs

Rongbao Li, Rachada Sirawaraporn, P. Chitnumsub et al. · Journal of Molecular Biology · 2000 · 205 citations

Life Sciences, Biochemistry, Medicinal Chemistry +14

Crystal structure of Mycobacterium tuberculosis 6-hydroxymethyl-7,8-dihydropteroate synthase in complex with pterin monophosphate: new insight into the enzymatic mechanism and sulfa-drug action

Arthur M. Baca, Rachada Sirawaraporn, S. Turley et al. · Journal of Molecular Biology · 2000 · 136 citations

Life Sciences, Biochemistry, Molecular Biology +13

The dihydrofolate reductase domain of Plasmodium falciparum thymidylate synthase-dihydrofolate reductase. Gene synthesis, expression, and anti-folate-resistant mutants.

Worachart Sirawaraporn, Phisit Prapunwattana, Rachada Sirawaraporn et al. · Journal of Biological Chemistry · 1993 · 102 citations · Full text

Life Sciences, Genetics, Molecular Biology +17

Docking and Database Screening Reveal New Classes of<i>Plasmodium</i><i>f</i><i>alciparum</i>Dihydrofolate Reductase Inhibitors

Giulio Rastelli, Sara Pacchioni, Worachart Sirawaraporn et al. · Journal of Medicinal Chemistry · 2003 · 83 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17