Oliver Hucke

Revealing Atropisomer Axial Chirality in Drug Discovery

Steven R. LaPlante, Paul Edwards, Lee D. Fader et al. · ChemMedChem · 2011 · 499 citations

Molecular Pharmacology, Medicinal Chemistry, Molecular Sciences +15

Discovery of a 1,5-dihydrobenzo[b][1,4]diazepine-2,4-dione series of inhibitors of HIV-1 capsid assembly

Lee D. Fader, Richard C. Bethell, Pierre Bonneau et al. · Bioorganic & Medicinal Chemistry Letters · 2010 · 104 citations

Combinatorial Chemistry, Medicinal Chemistry, Heterocyclic +8

Human Intestinal Transporter Database: QSAR Modeling and Virtual Profiling of Drug Uptake, Efflux and Interactions

Alexander Sedykh, Denis Fourches, Jianmin Duan et al. · Pharmaceutical Research · 2012 · 91 citations · Full text

Drug Target, Qsar Modeling, Medicine +8

The Protein Farnesyltransferase Inhibitor Tipifarnib as a New Lead for the Development of Drugs against Chagas Disease

Oliver Hucke, Michael H. Gelb, Christophe L. M. J. Verlinde et al. · Journal of Medicinal Chemistry · 2005 · 84 citations · Full text

Phosphatidylinositol 4-Kinase III Beta Is Essential for Replication of Human Rhinovirus and Its Inhibition Causes a Lethal Phenotype <i>In Vivo</i>

Catherine Spickler, Julie Lippens, Marie-Kristine Laberge et al. · Antimicrobial Agents and Chemotherapy · 2013 · 81 citations · Full text