Kiran Sakhuja

RNase H2 catalytic core Aicardi-Goutières syndrome–related mutant invokes cGAS–STING innate immune-sensing pathway in mice

Vladislav Pokatayev, Naushaba Hasin, Hyongi Chon et al. · The Journal of Experimental Medicine · 2016 · 230 citations · Full text

Sustained Human Factor VIII Expression in Hemophilia A Mice Following Systemic Delivery of a Gutless Adenoviral Vector

P. Seshidhar Reddy, Kiran Sakhuja, Shanthi Ganesh et al. · Molecular Therapy · 2002 · 117 citations

An Upstream Open Reading Frame and the Context of the Two AUG Codons Affect the Abundance of Mitochondrial and Nuclear RNase H1

Yutaka Suzuki, J. Bradley Holmes, Susana M. Cerritelli et al. · Molecular and Cellular Biology · 2010 · 93 citations · Full text

Nuclear Rnase H1, Chromatin, Mitochondrial Biogenesis +14

Primer retention owing to the absence of RNase H1 is catastrophic for mitochondrial DNA replication

J. Bradley Holmes, Gökhan Akman, Stuart Wood et al. · Proceedings of the National Academy of Sciences · 2015 · 90 citations · Full text

Optimization of the Generation and Propagation of Gutless Adenoviral Vectors

Kiran Sakhuja, P. Seshidhar Reddy, Shanthi Ganesh et al. · Human Gene Therapy · 2003 · 73 citations

Gutless Vector Propagation, Viral Replication, Engineering +15