Insulin crystallization depends on zinc transporter ZnT8 expression, but is not required for normal glucose homeostasis in mice

Katleen Lemaire, Magalie A. Ravier, Anica Schraenen, +10

Proceedings of the National Academy of Sciences

Ubiquitin Fold Modifier 1 (UFM1) and Its Target UFBP1 Protect Pancreatic Beta Cells from ER Stress-Induced Apoptosis

Katleen Lemaire, Rodrigo Ferreira de Moura, Mikaela Granvik, +7

PLoS ONE

Protein FunctionSignal TransductionSignaling PathwayMedicineNatural Sciences +13

Tissue-specific disallowance of housekeeping genes: The other face of cell differentiation

Lieven Thorrez, Ilaria Laudadio, Katrijn Van Deun, +14

Genome Research

Impaired Islet Function in Commonly Used Transgenic Mouse Lines due to Human Growth Hormone Minigene Expression

Bas Brouwers, Geoffroy de Faudeur, Anna B. Osipovich, +18

Cell Metabolism

Knockout MouseDevelopmental BiologyXenotransplantationTransgenic Mouse ModelsHuman Growth +9

Placental lactogens induce serotonin biosynthesis in a subset of mouse beta cells during pregnancy

Anica Schraenen, Katleen Lemaire, Geoffroy de Faudeur, +9

Diabetologia

β-Cell–Specific Gene Repression: A Mechanism to Protect Against Inappropriate or Maladjusted Insulin Secretion?

Frans Schuit, Leentje Van Lommel, Mikaela Granvik, +4

Diabetes

Maladjusted Insulin SecretionContinuous ProtectionInsulin SignalingMetabolic SyndromeTranscriptional Regulation +23

Mice Deficient in the Respiratory Chain Gene Cox6a2 Are Protected against High-Fat Diet-Induced Obesity and Insulin Resistance

Roel Quintens, Sarvjeet Singh, Katleen Lemaire, +19

PLoS ONE

Metabolic DisorderImmunologyInsulin SignalingOxidative StressComplex Iv +17

Prolactin Receptors and Placental Lactogen Drive Male Mouse Pancreatic Islets to Pregnancy-Related mRNA Changes

Lotte Goyvaerts, Katleen Lemaire, Ingrid Arijs, +7

PLoS ONE

ImmunologyGynecologyPancreas TransplantationReproductive BiologyPregnancy Mrna Profile +14

mRNA expression analysis of cell cycle genes in islets of pregnant mice

Anica Schraenen, Geoffroy de Faudeur, Lieven Thorrez, +6

Diabetologia

How stable is repression of disallowed genes in pancreatic islets in response to metabolic stress?

Katleen Lemaire, Mikaela Granvik, Anica Schraenen, +6

PLoS ONE