Anti-human CD117 CAR T-cells efficiently eliminate healthy and malignant CD117-expressing hematopoietic cells

Renier Myburgh, Jonathan D. Kiefer, Norman F. Russkamp, +13

Leukemia

Cell TherapyT-regulatory CellHematologyImmunologyAutoimmunity +4

An engineered protein antagonist of K-Ras/B-Raf interaction

Monique J. Kauke, Michael W. Traxlmayr, Jillian A. Parker, +6

Scientific Reports

Strong Enrichment of Aromatic Residues in Binding Sites from a Charge-neutralized Hyperthermostable Sso7d Scaffold Library

Michael W. Traxlmayr, Jonathan D. Kiefer, Raja Srinivas, +6

Journal of Biological Chemistry

Quantitative and Qualitative Analysis of Humoral Immunity Reveals Continued and Personalized Evolution in Chronic Viral Infection

Nike Julia Kräutler, Alexander Yermanos, Alessandro Pedrioli, +13

Cell Reports

Anti-CD117 immunotherapy to eliminate hematopoietic and leukemia stem cells

Norman F. Russkamp, Renier Myburgh, Jonathan D. Kiefer, +2

Experimental Hematology

A Fibrin-Specific Monoclonal Antibody from a Designed Phage Display Library Inhibits Clot Formation and Localizes to Tumors In Vivo

Alessia Putelli, Jonathan D. Kiefer, Matthias Zadory, +2

Journal of Molecular Biology

Immunocytochemical TechniqueImmunologyPathologyAntibody ScreeningAntibody Engineering +8

Generation of “LYmph Node Derived Antibody Libraries” (LYNDAL) for selecting fully human antibody fragments with therapeutic potential

Philipp Diebolder, Armin Keller, Stephanie Haase, +13

mAbs

Design Principles for SuCESsFul Biosensors: Specific Fluorophore/Analyte Binding and Minimization of Fluorophore/Scaffold Interactions

Seymour de Picciotto, Paige Dickson, Michael W. Traxlmayr, +9

Journal of Molecular Biology

EngineeringBiosensing SystemsBiomedical DiagnosticsSingle-molecule DetectionElectroanalytical Sensor +8

Targeted Delivery of TNF Potentiates the Antibody-Dependent Cell-Mediated Cytotoxicity of an Anti-Melanoma Immunoglobulin

Patrizia Murer, Jonathan D. Kiefer, Louis Plüss, +4

Journal of Investigative Dermatology

Cancer ImmunosurveillanceMedicineImmunologyImmune Checkpoint InhibitorImmunomodulation +7

Structures of designed armadillo repeat proteins binding to peptides fused to globular domains

Simon Hansen, Jonathan D. Kiefer, Chaithanya Madhurantakam, +2

Protein Science

Protein AssemblyPeptide EngineeringMolecular BiologyPeptide ScienceAnalytical Ultracentrifugation +18