Melanie Wurm

Biallelic mutations in PALB2 cause Fanconi anemia subtype FA-N and predispose to childhood cancer

Sarah Reid, Detlev Schindler, Helmut Hanenberg et al. · Nature Genetics · 2006 · 640 citations

Biallelic Mutations, Genetic Disorder, Genetics +6

Lightening up the UV response by identification of the arylhydrocarbon receptor as a cytoplasmatic target for ultraviolet B radiation

Ellen Fritsche, Claudia Schäfer, Christian Calles et al. · Proceedings of the National Academy of Sciences · 2007 · 433 citations · Full text

FANCI is a second monoubiquitinated member of the Fanconi anemia pathway

Ashley E Sims, Elizabeth Spiteri, Robert J. Sims et al. · Nature Structural & Molecular Biology · 2007 · 277 citations

Biology, Second Monoubiquitinated Member, Genetics +4

A selective and orally bioavailable VHL-recruiting PROTAC achieves SMARCA2 degradation in vivo

Christiane Kofink, Nicole Trainor, Barbara Mair et al. · Nature Communications · 2022 · 194 citations · Full text

Targeting cancer with small-molecule pan-KRAS degraders

Johannes Popow, William Farnaby, Andreas Gollner et al. · Science · 2024 · 130 citations · Full text

Tumor Biology, Genetic Kras Aberrations, Oncogenic Kras +15