Concepedia

Robert J. Sims

RJ

Statistics

Publications

36

Citations

5.5K

H-Index

26

Active since

1974

Affiliations

Constellation Pharmaceuticals (United States)(Current)

Massachusetts General Hospital

Howard Hughes Medical Institute

The University of Texas at Austin

Memorial Sloan Kettering Cancer Center

Robert J. Sims is an author at Constellation Pharmaceuticals (United States) specializing in life sciences, pharmacology, and molecular biology.

Publications per year

1974–2022

36

Publications

36

Targeting MYC dependence in cancer by inhibiting BET bromodomains

Jennifer A. Mertz, Andrew R. Conery, Barbara M. Bryant et al. · Proceedings of the National Academy of Sciences · 2011 · 1.1K citations · Full text

, , +17

Recognition of Trimethylated Histone H3 Lysine 4 Facilitates the Recruitment of Transcription Postinitiation Factors and Pre-mRNA Splicing

Robert J. Sims, Scott Millhouse, Chi-Fu Chen et al. · Molecular Cell · 2007 · 572 citations · Full text

, , +15

Human but Not Yeast CHD1 Binds Directly and Selectively to Histone H3 Methylated at Lysine 4 via Its Tandem Chromodomains

Robert J. Sims, Chi-Fu Chen, Helena Santos-Rosa et al. · Journal of Biological Chemistry · 2005 · 404 citations · Full text

, , +15

BRD4 is an atypical kinase that phosphorylates Serine2 of the RNA Polymerase II carboxy-terminal domain

Ballachanda N. Devaiah, Brian A. Lewis, Natasha Cherman et al. · Proceedings of the National Academy of Sciences · 2012 · 378 citations · Full text

, , +16

L3MBTL1, a Histone-Methylation-Dependent Chromatin Lock

Patrick Trojer, Guohong Li, Robert J. Sims et al. · Cell · 2007 · 339 citations

, , +11

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