Fiona Thistlethwaite

Involvement of Brca2 in DNA Repair

Ketan J. Patel, Veronica Yu, Hyun‐Sook Lee et al. · Molecular Cell · 1998 · 631 citations · Full text

Life Sciences, Genetics, Molecular Biology +12

Trastuzumab duocarmazine in locally advanced and metastatic solid tumours and HER2-expressing breast cancer: a phase 1 dose-escalation and dose-expansion study

Udai Banerji, Carla M.L. van Herpen, Cristina Saura et al. · The Lancet Oncology · 2019 · 565 citations · Full text

Medicine, Oncology, Pharmacology +17

The clinical efficacy of first-generation carcinoembryonic antigen (CEACAM5)-specific CAR T cells is limited by poor persistence and transient pre-conditioning-dependent respiratory toxicity

Fiona Thistlethwaite, David E. Gilham, Ryan D. Guest et al. · Cancer Immunology Immunotherapy · 2017 · 409 citations · Full text

Life Sciences, Immunology, Oncology +17

Utility of ctDNA to support patient selection for early phase clinical trials: the TARGET study

Dominic G. Rothwell, Mahmood Ayub, Natalie Cook et al. · Nature Medicine · 2019 · 306 citations · Full text

Medicine, Oncology, Radiology +10

Afamitresgene autoleucel for advanced synovial sarcoma and myxoid round cell liposarcoma (SPEARHEAD-1): an international, open-label, phase 2 trial

Sandra P. D’Angelo, Dejka M. Araujo, Albiruni R. Abdul Razak et al. · The Lancet · 2024 · 263 citations · Full text

Medicine, Oncology, Chemotherapy +13