Shobana Sekar

Alzheimer's disease is associated with altered expression of genes involved in immune response and mitochondrial processes in astrocytes

Shobana Sekar, Jacquelyn McDonald, Lori Cuyugan et al. · Neurobiology of Aging · 2014 · 216 citations · Full text

Engineering, Immunology, Laser Capture +24

Integrated genomic analyses reveal frequent <i>TERT</i> aberrations in acral melanoma

Winnie S. Liang, William P.D. Hendricks, Jeffrey Kiefer et al. · Genome Research · 2017 · 138 citations · Full text

Laser-captured microglia in the Alzheimer's and Parkinson's brain reveal unique regional expression profiles and suggest a potential role for hepatitis B in the Alzheimer's brain

Diego Mastroeni, Jennifer Nolz, Shobana Sekar et al. · Neurobiology of Aging · 2017 · 66 citations · Full text

Alzheimer's Disease, Medicine, Dementia +12

A phase I/II study of TKM-080301, a <i>PLK1</i>-targeted RNAi in patients with adrenocortical cancer (ACC).

Michael J. Demeure, Tannaz Armaghany, Samuel Ejadi et al. · Journal of Clinical Oncology · 2016 · 49 citations

Phase I/ii Study, Immunology, Refractory Acc +18

ANK1 is up-regulated in laser captured microglia in Alzheimer’s brain; the importance of addressing cellular heterogeneity

Diego Mastroeni, Shobana Sekar, Jennifer Nolz et al. · PLoS ONE · 2017 · 47 citations · Full text

Neurodegenerative Diseases, Alzheimer's Disease, Cellular Heterogeneity +14