George J. Kontoghiorghes

Effective chelation of iron in beta thalassaemia with the oral chelator 1,2-dimethyl-3-hydroxypyrid-4-one.

George J. Kontoghiorghes, M. A. Aldouri, A. V. Hoffbrand et al. · BMJ · 1987 · 190 citations · Full text

Medicine, Hematology, Pharmacology +17

Redox Interactions of Vitamin C and Iron: Inhibition of the Pro-Oxidant Activity by Deferiprone

Viktor A. Timoshnikov, Tatyana V. Kobzeva, Nikolay E. Polyakov et al. · International Journal of Molecular Sciences · 2020 · 160 citations · Full text

Life Sciences, Biochemistry, Nutritional Sciences +17

Pharmacokinetic studies in humans with the oral iron chelator 1,2-dimethyl-3-hydroxypyrid-4-one

George J. Kontoghiorghes, John Goddard, A Bartlett et al. · Clinical Pharmacology & Therapeutics · 1990 · 134 citations

Medicine, Clinical Pharmacokinetics, Pharmacology +17

Long‐term trial with the oral iron chelator 1,2‐dimethyl‐3‐hydroxypyrid‐4‐one (L₁) I. IRON CHELATION AND METABOLIC STUDIES

George J. Kontoghiorghes, A Bartlett, A. V. Hoffbrand et al. · British Journal of Haematology · 1990 · 127 citations

Medicine, Pharmacokinetics, Pharmacology +16

Simple synthesis of the potent iron chelators 1-alkyl-3-hydroxy-2-methylpyrid-4-ones

George J. Kontoghiorghes, L Sheppard · Inorganica Chimica Acta · 1987 · 104 citations

Natural Sciences, Chemistry, Medicinal Chemistry +9