Zihuai He

Organ aging signatures in the plasma proteome track health and disease

Hamilton Oh, Jarod Rutledge, Daniel Nachun et al. · Nature · 2023 · 475 citations · Full text

Molecular signatures underlying neurofibrillary tangle susceptibility in Alzheimer’s disease

Marcos Otero‐García, Sameehan Mahajani, Debia Wakhloo et al. · Neuron · 2022 · 201 citations · Full text

Neurodegenerative Diseases, Alzheimer's Disease, Molecular Neuroscience +10

Multiple causal variants underlie genetic associations in humans

Nathan S. Abell, Marianne K. DeGorter, Michael J. Gloudemans et al. · Science · 2022 · 191 citations · Full text

Genetics, Genetic Epidemiology, Tight Ld +16

FUN-LDA: A Latent Dirichlet Allocation Model for Predicting Tissue-Specific Functional Effects of Noncoding Variation: Methods and Applications

Daniel Backenroth, Zihuai He, Krzysztof Kiryluk et al. · The American Journal of Human Genetics · 2018 · 85 citations · Full text

Latent Modeling, Engineering, Topic Model +11

Association of Rare <i>APOE</i> Missense Variants V236E and R251G With Risk of Alzheimer Disease

Yann Le Guen, Michaël E. Belloy, Benjamin Grenier‐Boley et al. · JAMA Neurology · 2022 · 82 citations · Full text