Yann Le Guen

Organ aging signatures in the plasma proteome track health and disease

Hamilton Oh, Jarod Rutledge, Daniel Nachun et al. · Nature · 2023 · 573 citations · Full text

Life Sciences, Neuroscience, Physiology +16

Prevalence, associated factors and outcomes of pressure injuries in adult intensive care unit patients: the DecubICUs study

Sonia Labeau, Elsa Afonso, Julie Benbenishty et al. · Intensive Care Medicine · 2020 · 330 citations · Full text

Medicine, Surgery, Emergency Surgery +13

<i>APOE</i> Genotype and Alzheimer Disease Risk Across Age, Sex, and Population Ancestry

Michaël E. Belloy, Shea J. Andrews, Yann Le Guen et al. · JAMA Neurology · 2023 · 280 citations · Full text

Medicine, Genetics, Neurology +17

Exome sequencing identifies rare damaging variants in ATP8B4 and ABCA1 as risk factors for Alzheimer’s disease

Henne Holstege, Marc Hulsman, Camille Charbonnier et al. · Nature Genetics · 2022 · 219 citations · Full text

Life Sciences, Genetics, Molecular Genetics +17

Association of<i>Klotho</i>-VS Heterozygosity With Risk of Alzheimer Disease in Individuals Who Carry<i>APOE4</i>

Michaël E. Belloy, Valerio Napolioni, Summer S. Han et al. · JAMA Neurology · 2020 · 116 citations · Full text

Medicine, Genetics, Neurology +17