A single-cell transcriptomic atlas characterizes ageing tissues in the mouse

Nicole Almanzar, Jane Antony, Ankit S. Baghel, +131

Nature

Cell LineageDevelopmental BiologySingle-cell Transcriptomic AtlasSingle Cell SequencingMedicine +6

Ageing hallmarks exhibit organ-specific temporal signatures

Nicholas Schaum, Benoit Lehallier, Oliver Hãhn, +158

Nature

Signal TransductionAgingDevelopmental BiologyLongevityCellular Senescence +5

The kinesin-4 protein Kif7 regulates mammalian Hedgehog signalling by organizing the cilium tip compartment

Mu He, Radhika Subramanian, Fiona Bangs, +4

Nature Cell Biology

Protein FunctionSignal TransductionDevelopmental BiologySignaling PathwayMammalian Hedgehog Signalling +9

Mouse Kif7/Costal2 is a cilia-associated protein that regulates Sonic hedgehog signaling

Karel F. Liem, Mu He, Polloneal Jymmiel R. Ocbina, +1

Proceedings of the National Academy of Sciences

Cilia-associated ProteinKnockout MouseCell LineageSignal TransductionDevelopmental Biology +13

The IFT-A complex regulates Shh signaling through cilia structure and membrane protein trafficking

Karel F. Liem, Alyson Ashe, Mu He, +5

The Journal of Cell Biology

Membrane Protein TraffickingGeneticsIntraflagellar TransportCytoskeletonCilia Structure +15

Protein kinase A acts at the basal body of the primary cilium to prevent Gli2 activation and ventralization of the mouse neural tube

Miquel Tuson, Mu He, Kathryn V. Anderson

Development

Primary CiliumCellular NeurobiologyCellular PhysiologySonic HedgehogSignaling Pathway +15

Thermal Allylations of Aldehydes with a Fluorous Allylstannane. Separation of Organic and Fluorous Products by Solid Phase Extraction with Fluorous Reverse Phase Silica Gel

Dennis P. Curran, Sabine Hadidaꝉ, Mu He

The Journal of Organic Chemistry

Solvent ExtractionChemical EngineeringIndustrial ChemistryEngineeringSelective Separation +10

Molecular hallmarks of heterochronic parabiosis at single-cell resolution

Róbert Pálovics, Andreas Keller, Nicholas Schaum, +138

Nature

Synthesis of IL-6 by Hepatocytes Is a Normal Response to Common Hepatic Stimuli

Callie A. Norris, Mu He, Liang‐I Kang, +10

PLoS ONE

ImmunologyCell DeathImmunologic MechanismCommon Hepatic StimuliCholangiopathies +21

Multi-scale spatial heterogeneity enhances particle clearance in airway ciliary arrays

Guillermina R. Ramirez-San Juan, Arnold J. T. M. Mathijssen, Mu He, +3

Nature Physics

Lung DepositionBiophysicsRadiologyAirway Ciliary Arrays