Jonathan J. Mills

Discovery of Potent Myeloid Cell Leukemia-1 (Mcl-1) Inhibitors That Demonstrate in Vivo Activity in Mouse Xenograft Models of Human Cancer

Taekyu Lee, Plamen P. Christov, Subrata Shaw et al. · Journal of Medicinal Chemistry · 2019 · 64 citations · Full text

Hematological Malignancy, Tumor Biology, Mouse Xenograft Models +15

Discovery and Structure-Based Optimization of Potent and Selective WD Repeat Domain 5 (WDR5) Inhibitors Containing a Dihydroisoquinolinone Bicyclic Core

Jianhua Tian, Kevin B. Teuscher, Erin R. Aho et al. · Journal of Medicinal Chemistry · 2019 · 59 citations · Full text

Molecular Docking, Combinatorial Chemistry, Medicinal Chemistry +15

Fragment-based screening of programmed death ligand 1 (PD-L1)

Evan Perry, Jonathan J. Mills, Bin Zhao et al. · Bioorganic & Medicinal Chemistry Letters · 2019 · 55 citations · Full text

Molecular Docking, Medicinal Chemistry, Drug Target +6

Discovery of Potent Orally Bioavailable WD Repeat Domain 5 (WDR5) Inhibitors Using a Pharmacophore-Based Optimization

Kevin B. Teuscher, Kenneth M. Meyers, Qiangqiang Wei et al. · Journal of Medicinal Chemistry · 2022 · 31 citations · Full text

Fragment-Based Discovery of Small Molecules Bound to T-Cell Immunoglobulin and Mucin Domain-Containing Molecule 3 (TIM-3)

Tyson A. Rietz, Kevin B. Teuscher, Jonathan J. Mills et al. · Journal of Medicinal Chemistry · 2021 · 30 citations · Full text

T-regulatory Cell, Immunology, Molecular Biology +21