Efficient generation of Rosa26 knock-in mice using CRISPR/Cas9 in C57BL/6 zygotes

Van Trung Chu, Timm Weber, Robin Graf, +6

BMC Biotechnology

PI3 Kinase and FOXO1 Transcription Factor Activity Differentially Control B Cells in the Germinal Center Light and Dark Zones

Sandrine Sander, Van Trung Chu, Tomoharu Yasuda, +9

Immunity

Pi3 KinaseSignal TransductionDevelopmental BiologySignaling PathwayCell Regulation +10

Efficient CRISPR-mediated mutagenesis in primary immune cells using CrispRGold and a C57BL/6 Cas9 transgenic mouse line

Van Trung Chu, Robin Graf, Tristan Wirtz, +9

Proceedings of the National Academy of Sciences

sgRNA Sequence Motifs Blocking Efficient CRISPR/Cas9-Mediated Gene Editing

Robin Graf, Xun Li, Van Trung Chu, +1

Cell Reports

GeneticsGenetic EngineeringGene EditingGenome EditingGene Expression +2

BCR-dependent lineage plasticity in mature B cells

Robin Graf, Jane Seagal, Kevin L. Otipoby, +6

Science

Identification of LIN28B-bound mRNAs reveals features of target recognition and regulation

Robin Graf, Mathias Munschauer, Guido Mastrobuoni, +5

RNA Biology

Rna ProcessingTranscriptional RegulationMedicineGeneticsRna Biology +13

Precise CRISPR-Cas–mediated gene repair with minimal off-target and unintended on-target mutations in human hematopoietic stem cells

Ngoc Tung Tran, Eric Danner, Xun Li, +6

Science Advances

CRISPR-Cas9-Mediated ELANE Mutation Correction in Hematopoietic Stem and Progenitor Cells to Treat Severe Congenital Neutropenia

Ngoc Tung Tran, Robin Graf, Annika Wulf-Goldenberg, +6

Molecular Therapy

Efficient CRISPR/Cas9-Mediated Gene Knockin in Mouse Hematopoietic Stem and Progenitor Cells

Ngoc Tung Tran, Thomas Sommermann, Robin Graf, +6

Cell Reports

B-Cell-Specific Myd88 L252P Expression Causes a Premalignant Gammopathy Resembling IgM MGUS

Kristin Schmidt, Ulrike Sack, Robin Graf, +6

Frontiers in Immunology