Tracking germinal center B cells expressing germ-line immunoglobulin γ1 transcripts by conditional gene targeting

Stefano Casola, Giorgio Cattoretti, Nathalie Uyttersprot, +7

Proceedings of the National Academy of Sciences

Fas Receptor Expression in Germinal-Center B Cells Is Essential for T and B Lymphocyte Homeostasis

Zhenyue Hao, Gordon S. Duncan, Jane Seagal, +12

Immunity

Germinal-center B CellsAutoimmune DiseaseLymphocyte DevelopmentMedicineAdaptive Immune System +11

Constitutive Canonical NF-κB Activation Cooperates with Disruption of BLIMP1 in the Pathogenesis of Activated B Cell-like Diffuse Large Cell Lymphoma

Dinis Pedro Calado, Baochun Zhang, Lakshmi Srinivasan, +8

Cancer Cell

Lymphoid NeoplasiaImmune Cell DevelopmentImmunologyTumor ImmunityPathology +7

Tumor-conditional anti-CTLA4 uncouples antitumor efficacy from immunotherapy-related toxicity

Chien-Chun Steven Pai, Donald M. Simons, Xiaoqing Lu, +22

Journal of Clinical Investigation

Clonal Deletion of Tumor-Specific T Cells by Interferon-γ Confers Therapeutic Resistance to Combination Immune Checkpoint Blockade

Chien-Chun Steven Pai, John Huang, Xiaoqing Lu, +24

Immunity

Tumor-specific T CellsTumor ImmunologyCancer ImmunosurveillanceClonal DeletionImmunology +8

LMP1 signaling can replace CD40 signaling in B cells in vivo and has unique features of inducing class-switch recombination to IgG1

Rastelli Julia, Hömig-Hölzel Cornelia, Jane Seagal, +4

Blood

IgG1 B cell receptor signaling is inhibited by CD22 and promotes the development of B cells whose survival is less dependent on Igα/β

Ari Waisman, Manfred Kraus, Jane Seagal, +8

The Journal of Experimental Medicine

Lymphocyte DevelopmentImmunologyImmune RegulationImmunologic MechanismB Cell Development +16

BCR-dependent lineage plasticity in mature B cells

Robin Graf, Jane Seagal, Kevin L. Otipoby, +6

Science

Structural basis for continued antibody evasion by the SARS-CoV-2 receptor binding domain

Katherine Nabel Smith, Sarah A. Clark, Sundaresh Shankar, +28

Science

Dominant StrainsImmunologyViral PathogenesisMolecular BiologyViral Structural Protein +14

Vascular Endothelial Growth Factor and Angiopoietin in Liver Regeneration

Yehudit Kraizer, Nidal Mawasi, Jane Seagal, +3

Biochemical and Biophysical Research Communications

AngiogenesisHepatologyDevelopmental BiologyLiver PhysiologyVascular Endothelial Growth Factor +7