Michael L. Homiski

Discovery of Two Clinical Histamine H ₃ Receptor Antagonists: <i>trans</i> - <i>N</i> -Ethyl-3-fluoro-3-[3-fluoro-4-(pyrrolidinylmethyl)phenyl]cyclobutanecarboxamide (PF-03654746) and <i>trans</i> -3-Fluoro-3-[3-fluoro-4-(pyrrolidin-1-ylmethyl)phenyl]- <i>N</i> -(2-methylpropyl)cyclobutanecarboxamide (PF-03654764)

Travis T. Wager, Betty Pettersen, Anne W. Schmidt et al. · Journal of Medicinal Chemistry · 2011 · 108 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

Yeast DEL assay detects clastogens

Zhanna Kirpnick, Michael L. Homiski, Elizabeth Rubitski et al. · Mutation Research/Genetic Toxicology and Environmental Mutagenesis · 2005 · 43 citations

Agriculture, Microbiology, Molecular Biology +7

Development and validation of an in vitro micronucleus assay platform in TK6 cells

Zhanna Sobol, Michael L. Homiski, Donna Dickinson et al. · Mutation Research/Genetic Toxicology and Environmental Mutagenesis · 2012 · 39 citations

Pharmacy, Cell Biology, Molecular Biology +10

Assessing the genotoxicity of <i>N</i>‐nitrosodiethylamine with three in vivo endpoints in male Big Blue® transgenic and wild‐type <scp>C</scp>57<scp>BL</scp>/6<scp>N</scp> mice

Shaofei Zhang, Stephanie L. Coffing, William C. Gunther et al. · Environmental and Molecular Mutagenesis · 2024 · 15 citations · Full text

Pharmacy, Pharmacology, Toxicology +10

Concordance analysis of an in vitro micronucleus screening assay and the regulatory chromosome aberration assay using pharmaceutical drug candidates

Michael L. Homiski, Paula A. Muehlbauer, Krista L. Dobo et al. · Environmental and Molecular Mutagenesis · 2009 · 11 citations

Pharmacy, Pharmacology, Toxicology +16