Kostas Vekrellis

Cell-Produced α-Synuclein Is Secreted in a Calcium-Dependent Manner by Exosomes and Impacts Neuronal Survival

Evangelia Emmanouilidou, Katerina Melachroinou, Theodoros I. Roumeliotis et al. · Journal of Neuroscience · 2010 · 1.1K citations · Full text

Protein Secretion, Calcium-dependent Manner, Cellular Neurobiology +21

Wild Type α-Synuclein Is Degraded by Chaperone-mediated Autophagy and Macroautophagy in Neuronal Cells

Tereza Vogiatzi, Maria Xilouri, Kostas Vekrellis et al. · Journal of Biological Chemistry · 2008 · 654 citations · Full text

Cell Autophagy, Neurodegenerative Diseases, Mitophagy +13

ER Stress and Autophagic Perturbations Lead to Elevated Extracellular α-Synuclein in GBA-N370S Parkinson's iPSC-Derived Dopamine Neurons

Hugo J. R. Fernandes, Elizabeth M. Hartfield, Helen Christian et al. · Stem Cell Reports · 2016 · 350 citations · Full text

Abberant α-Synuclein Confers Toxicity to Neurons in Part through Inhibition of Chaperone-Mediated Autophagy

Maria Xilouri, Tereza Vogiatzi, Kostas Vekrellis et al. · PLoS ONE · 2009 · 344 citations · Full text

Autophagy inhibition promotes SNCA/alpha-synuclein release and transfer via extracellular vesicles with a hybrid autophagosome-exosome-like phenotype

Georgia Minakaki, Stefanie Menges, Ágnes Kittel et al. · Autophagy · 2017 · 249 citations · Full text

Mitophagy, Snca Release, Immunology +17