Helen Christian

LRRK2 regulates autophagic activity and localizes to specific membrane microdomains in a novel human genomic reporter cellular model

Javier Alegre‐Abarrategui, Helen Christian, Michele MP Lufino et al. · Human Molecular Genetics · 2009 · 436 citations · Full text

Life Sciences, Cell Biology, Neuroscience +17

ER Stress and Autophagic Perturbations Lead to Elevated Extracellular α-Synuclein in GBA-N370S Parkinson's iPSC-Derived Dopamine Neurons

Hugo J. R. Fernandes, Elizabeth M. Hartfield, Helen Christian et al. · Stem Cell Reports · 2016 · 365 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

The Role of the Aryl Hydrocarbon Receptor-Interacting Protein Gene in Familial and Sporadic Pituitary Adenomas

Chrysanthia A. Leontiou, Maria Gueorguiev, Jacqueline van der Spuy et al. · The Journal of Clinical Endocrinology & Metabolism · 2008 · 294 citations · Full text

Medicine, Endocrinology, Molecular Genetics +17

<i>C9orf72</i> Hexanucleotide Expansions Are Associated with Altered Endoplasmic Reticulum Calcium Homeostasis and Stress Granule Formation in Induced Pluripotent Stem Cell-Derived Neurons from Patients with Amyotrophic Lateral Sclerosis and Frontotemporal Dementia

Ruxandra Dafinca, Jakub Scaber, Nidaa A. Ababneh et al. · Stem Cells · 2016 · 244 citations · Full text

Life Sciences, Genetics, Neuroscience +17

Cardiac ferroportin regulates cellular iron homeostasis and is important for cardiac function

Samira Lakhal‐Littleton, Magda Wolna, Carolyn A. Carr et al. · Proceedings of the National Academy of Sciences · 2015 · 235 citations · Full text

Medicine, Cardiology, Physiology +16