Gert Kiss

Computational Design of an Enzyme Catalyst for a Stereoselective Bimolecular Diels-Alder Reaction

Justin B. Siegel, Alexandre Zanghellini, Helena M. Lovick et al. · Science · 2010 · 917 citations

Bioorganic Chemistry, Engineering, Biochemistry +15

RAS nucleotide cycling underlies the SHP2 phosphatase dependence of mutant BRAF-, NF1- and RAS-driven cancers

Robert J. Nichols, Franziska Haderk, Carlos Stahlhut et al. · Nature Cell Biology · 2018 · 407 citations · Full text

Ras-driven Cancers, Tumor Biology, Mutant Braf- +9

Iterative approach to computational enzyme design

Heidi K. Privett, Gert Kiss, Toni M. Lee et al. · Proceedings of the National Academy of Sciences · 2012 · 334 citations · Full text

Engineering, Protein Assembly, Molecular Biology +16

Bridging the gaps in design methodologies by evolutionary optimization of the stability and proficiency of designed Kemp eliminase KE59

Olga Khersonsky, Gert Kiss, Daniela Röthlisberger et al. · Proceedings of the National Academy of Sciences · 2012 · 237 citations · Full text

Optimization of the In-Silico-Designed Kemp Eliminase KE70 by Computational Design and Directed Evolution

Olga Khersonsky, Daniela Röthlisberger, Andrew M. Wollacott et al. · Journal of Molecular Biology · 2011 · 179 citations · Full text

Electrical Engineering, Engineering, Directed Evolution +2