Jodie Manini

Potent and Efficacious Inhibition of CXCR2 Signaling by Biparatopic Nanobodies Combining Two Distinct Modes of Action

ME Bradley, Bruno Dombrecht, Jodie Manini et al. · Molecular Pharmacology · 2014 · 91 citations · Full text

Life Sciences, Immunology, Pharmacology +17

SB265610 is an allosteric, inverse agonist at the human CXCR2 receptor

ME Bradley, ME Bond, Jodie Manini et al. · British Journal of Pharmacology · 2009 · 57 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17

7-Azaindole-3-acetic acid derivatives: Potent and selective CRTh2 receptor antagonists

David A. Sandham, Claire Adcock, Kamlesh Bala et al. · Bioorganic & Medicinal Chemistry Letters · 2009 · 44 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +7

Discovery of Fevipiprant (NVP-QAW039), a Potent and Selective DP₂ Receptor Antagonist for Treatment of Asthma

David A. Sandham, Lucy Barker, Lyndon Brown et al. · ACS Medicinal Chemistry Letters · 2017 · 35 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +11

Discovery and characterization of NVP-QAV680, a potent and selective CRTh2 receptor antagonist suitable for clinical testing in allergic diseases

David A. Sandham, Nicola Arnold, Heinrich Aschauer et al. · Bioorganic & Medicinal Chemistry · 2013 · 22 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +9