David L. Prole

IP3 Receptors Preferentially Associate with ER-Lysosome Contact Sites and Selectively Deliver Ca2+ to Lysosomes

Peace Atakpa, Nagendra Babu Thillaiappan, Stefania Mataragka et al. · Cell Reports · 2018 · 176 citations · Full text

Red fluorescent genetically encoded Ca2+ indicators for use in mitochondria and endoplasmic reticulum

Jiahui Wu, David L. Prole, Yi Shen et al. · Biochemical Journal · 2014 · 171 citations · Full text

Molecular Biology, Synaptic Signaling, Redox Biology +24

An NAADP-gated Two-pore Channel Targeted to the Plasma Membrane Uncouples Triggering from Amplifying Ca2+ Signals

Eugen Brailoiu, Taufiq Rahman, Dev Churamani et al. · Journal of Biological Chemistry · 2010 · 167 citations · Full text

Naadp-gated Two-pore Channel, Molecular Biology, Biomedical Engineering +20

Ca2+ signals initiate at immobile IP3 receptors adjacent to ER-plasma membrane junctions

Nagendra Babu Thillaiappan, Alap P. Chavda, Stephen C. Tovey et al. · Nature Communications · 2017 · 155 citations · Full text

Lysosomes shape Ins(1,4,5)<i>P</i>3-evoked Ca2+ signals by selectively sequestering Ca2+ released from the endoplasmic reticulum

Cristina I. López-Sanjurjo, Stephen C. Tovey, David L. Prole et al. · Journal of Cell Science · 2012 · 138 citations · Full text

Molecular Biology, Cytoskeleton, Synaptic Signaling +25