In vivo effects of a GPR30 antagonist

Megan K. Dennis, Ritwik Burai, Chinnasamy Ramesh, +13

Nature Chemical Biology

Functional SelectivityMedicinePharmacological AgentNeuropharmacologyExperimental Pharmacology +3

Distribution and characterization of estrogen receptor G protein-coupled receptor 30 in the rat central nervous system

Eugen Brailoiu, Siok L. Dun, G. Cristina Brailoiu, +5

Journal of Endocrinology

Essential requirement for two-pore channel 1 in NAADP-mediated calcium signaling

Eugen Brailoiu, Dev Churamani, Xinjiang Cai, +8

The Journal of Cell Biology

Signal TransductionMolecular PhysiologyHyperpolarization (Biology)G Protein-coupled ReceptorCell Signaling +13

Regulatory Role of G Protein–Coupled Estrogen Receptor for Vascular Function and Obesity

Elvira Haas, Indranil Bhattacharya, Eugen Brailoiu, +17

Circulation Research

Nesfatin-1: Distribution and Interaction with a G Protein-Coupled Receptor in the Rat Brain

G. Cristina Brailoiu, Siok L. Dun, Eugen Brailoiu, +4

Endocrinology

The G Protein–Coupled Receptor GPR30 Inhibits Proliferation of Estrogen Receptor–Positive Breast Cancer Cells

Eric A. Ariazi, Eugen Brailoiu, Smitha Yerrum, +10

Cancer Research

Activate Gpr30Breast OncologyG Protein-coupled ReceptorMedicineHormonal Receptor +11

Convergent regulation of the lysosomal two-pore channel-2 by Mg2+, NAADP, PI(3,5)P2 and multiple protein kinases

Ashutosh Kumar Jha, Manuj Ahuja, Sandip Patel, +2

The EMBO Journal

Molecular PhysiologySignal TransductionLysosomal Two-pore Channel-2Molecular BiologyConvergent Regulation +8

Dysregulation of lysosomal morphology by pathogenic LRRK2 is corrected by two-pore channel 2 inhibition

Leanne N. Hockey, Bethan S. Kilpatrick, Emily R. Eden, +7

Journal of Cell Science

An NAADP-gated Two-pore Channel Targeted to the Plasma Membrane Uncouples Triggering from Amplifying Ca2+ Signals

Eugen Brailoiu, Taufiq Rahman, Dev Churamani, +5

Journal of Biological Chemistry

Naadp-gated Two-pore ChannelMolecular BiologyBiomedical EngineeringCellular PhysiologyAcidic Organelles +18

Photoaffinity Labeling of Nicotinic Acid Adenine Dinucleotide Phosphate (NAADP) Targets in Mammalian Cells*

Yaping Lin-Moshier, Timothy F. Walseth, Dev Churamani, +6

Journal of Biological Chemistry