Takahiro Seki

Monitoring Drug Target Engagement in Cells and Tissues Using the Cellular Thermal Shift Assay

Daniel Martinez Molina, Rozbeh Jafari, Marina Ignatushchenko et al. · Science · 2013 · 2.1K citations

Molecular Docking, Target Engagement, Drug Target +14

Pericyte–fibroblast transition promotes tumor growth and metastasis

Kayoko Hosaka, Yunlong Yang, Takahiro Seki et al. · Proceedings of the National Academy of Sciences · 2016 · 399 citations · Full text

Cancer Lipid Metabolism Confers Antiangiogenic Drug Resistance

Hideki Iwamoto, Mitsuhiko Abe, Yunlong Yang et al. · Cell Metabolism · 2018 · 289 citations · Full text

Medicine, Pharmacology, Anti-cancer Agent +3

Brown-fat-mediated tumour suppression by cold-altered global metabolism

Takahiro Seki, Yunlong Yang, Xiaoting Sun et al. · Nature · 2022 · 259 citations · Full text

Cold-induced activation of brown adipose tissue and adipose angiogenesis in mice

Sharon Lim, Jennifer Honek, Yuan Xue et al. · Nature Protocols · 2012 · 227 citations · Full text

Inflammation, Metabolic Syndrome, Adipose Angiogenesis +14