Lynn E. Macdonald

High-throughput engineering of the mouse genome coupled with high-resolution expression analysis

David M. Valenzuela, Andrew Murphy, David Frendewey et al. · Nature Biotechnology · 2003 · 585 citations

Engineering, Transgenic Mouse Models, Molecular Biology +17

Mice with megabase humanization of their immunoglobulin genes generate antibodies as efficiently as normal mice

Andrew Murphy, Lynn E. Macdonald, Sean Stevens et al. · Proceedings of the National Academy of Sciences · 2014 · 439 citations · Full text

Genetic Humanization, Engineering, Transgenic Mouse Models +22

Precise and in situ genetic humanization of 6 Mb of mouse immunoglobulin genes

Lynn E. Macdonald, Margaret Karow, Sean Stevens et al. · Proceedings of the National Academy of Sciences · 2014 · 376 citations · Full text

A G Protein-coupled Receptor for UDP-glucose

Jon Chambers, Lynn E. Macdonald, Henry M. Sarau et al. · Journal of Biological Chemistry · 2000 · 341 citations · Full text

Humanized mouse model supports development, function, and tissue residency of human natural killer cells

Dietmar Herndler‐Brandstetter, Liang Shan, Yi Yao et al. · Proceedings of the National Academy of Sciences · 2017 · 167 citations · Full text