Geoffrey R. Fisher

DNA strand scission and free radical production in menadione-treated cells. Correlation with cytotoxicity and role of NADPH quinone acceptor oxidoreductase.

Louise M. Nutter, E O Ngo, Geoffrey R. Fisher et al. · Journal of Biological Chemistry · 1992 · 137 citations · Full text

Dna Damage, Lipid Peroxidation, Menadione-treated Cells +17

NAD(P)H (quinone acceptor) oxidoreductase (DT-diaphorase)-mediated two-electron reduction of anthraquinone-based antitumour agents and generation of hydroxyl radicals

Geoffrey R. Fisher, Peter L. Gutiérrez, Mark A. Oldcorne et al. · Biochemical Pharmacology · 1992 · 37 citations

Pharmaceutical Chemistry, Bioorganic Chemistry, Aldehyde Dehydrogenase +13

Free radical formation and DNA strand breakage during metabolism of diaziquone by NAD(P)H quinone-acceptor oxidoreductase (DT-diaphorase) and NADPH cytochrome c reductase

Geoffrey R. Fisher, Peter L. Gutiérrez · Free Radical Biology and Medicine · 1991 · 37 citations

Aldo-keto Reductase, Aldehyde Dehydrogenase, Biochemistry +11

Resistance to oxidants associated with elevated catalase activity in HL-60 leukemia cells that overexpress multidrug-resistance protein does not contribute to the resistance to daunorubicin manifested by these cells

Peter F. Lenehan, Peter L. Gutiérrez, John L. Wagner et al. · Cancer Chemotherapy and Pharmacology · 1995 · 35 citations

Biochemistry, Medicine, Catabolism +9

Involvement of Hydroxyl Radical Formation and Dna Strand Breakage in the Cytotoxicity of Anthraquinone Antitumour Agents

Geoffrey R. Fisher, Jeffrey Brown, L. H. Patterson · Free Radical Research Communications · 1990 · 32 citations

Aldo-keto Reductase, Id50 Values, Molecular Biology +22