alpha-Ketoacids scavenge H2O2 in vitro and in vivo and reduce menadione-induced DNA injury and cytotoxicity

Karl A. Nath, E O Ngo, Robert P. Hebbel, +3

American Journal of Physiology-Cell Physiology

Reductive StressBiochemistryMitochondrial FunctionMedicineLipid Peroxidation +13

DNA strand scission and free radical production in menadione-treated cells. Correlation with cytotoxicity and role of NADPH quinone acceptor oxidoreductase.

Louise M. Nutter, E O Ngo, Geoffrey R. Fisher, +1

Journal of Biological Chemistry

Dna DamageLipid PeroxidationMenadione-treated CellsFree Radical ProductionRedox Biology +15

An o-quinone form of estrogen produces free radicals in human breast cancer cells: Correlation with DNA damage

Louise M. Nutter, Yu Ying Wu, Emily O. Ngo, +3

Chemical Research in Toxicology

O-quinone FormDna DamageBiochemistryRadical (Chemistry)Mcf-7 Cells +12

Menadione: Spectrum of anticancer activity and effects on nucleotide metabolism in human neoplastic cell lines

Louise M. Nutter, Cheng Ann-Lii, Hsiao-Ling Hung, +3

Biochemical Pharmacology

Steroid MetabolismChemoprevention StrategyMalignant DiseaseMedicinePharmacology +10

Characterization of DNA damage induced by 3,4-estrone-o-quinone in human cells.

Louise M. Nutter, E O Ngo, Yusuf J. Abul‐Hajj

Journal of Biological Chemistry

Dna DamageMolecular BiologyTumor BiologyToxicological MechanismOxidative Stress +16

Menadione-induced DNA damage in a human tumor cell line

Emily O. Ngo, Ter-Ping Sun, Jang‐Yang Chang, +4

Biochemical Pharmacology

Tumor BiologyDna DamageOncogenic AgentMenadione-induced Dna DamageAnti-cancer Agent +5

Effect of pyruvate on oxidant injury to isolated and cellular DNA

Karl A. Nath, H Enright, Louise M. Nutter, +3

Kidney International

Reductive StressDna DamageOxidant InjuryBiochemistryNatural Sciences +11

Absence of Pyridoxine-5‘-Phosphate Oxidase (PNPO) Activity in Neoplastic Cells:  Isolation, Characterization, and Expression of PNPO cDNA

Emily O. Ngo, Garrett R. LePage, John W. Thanassi, +2

Biochemistry

Cell DeathNeurochemical BiomarkersAuthentic Pnpo CdnaRedox BiologyTumor Biology +17

Demonstration of viral thymidine kinase inhibitor and its effect on deoxynucleotide metabolism in cells infected with herpes simplex virus

Louise M. Nutter, Susan P. Grill, Ginger E. Dutschman, +3

Antimicrobial Agents and Chemotherapy

Dttp PoolsViral ReplicationImmunologyMolecular BiologyAntiviral Drug +16

Induction of virus enzymes by phorbol esters and n-butyrate in Epstein-Barr virus genome-carrying Raji cells.

Louise M. Nutter, Susan P. Grill, Jin-sen Li, +2

PubMed

Viral ReplicationMolecular VirologyEpstein-barr VirusEbv Enzyme ActivitiesPathogenesis +12