L. H. Patterson

The cancer preventative agent resveratrol is converted to the anticancer agent piceatannol by the cytochrome P450 enzyme CYP1B1

Gerard A. Potter, L. H. Patterson, E Wanogho et al. · British Journal of Cancer · 2002 · 375 citations · Full text

Medicine, Biochemistry, Pharmacology +17

Characterization of Changes in the Proteome in Different Regions of 3D Multicell Tumor Spheroids

Kathryn McMahon, Milène Volpato, Hassan Alshymaa Y et al. · Journal of Proteome Research · 2012 · 67 citations

Life Sciences, Cell Biology, Oncology +17

Glutathione S-transferase (GST) expression in the human hookworm Necator americanus: potential roles for excretory-secretory forms of GST

Peter M. Brophy, L. H. Patterson, Alan Brown et al. · Acta Tropica · 1995 · 47 citations

Life Sciences, Biochemistry, Entomology +16

The use of pharmacokinetic and pharmacodynamic end points to determine the dose of AQ4N, a novel hypoxic cell cytotoxin, given with fractionated radiotherapy in a phase I study

William P. Steward, Mark R. Middleton, A. Benghiat et al. · Annals of Oncology · 2007 · 44 citations

Medicine, Oncology, Pharmacology +14

Tumor-selective drug activation: a GDEPT approach utilizing cytochrome P450 1A1 and AQ4N

Anita Yakkundi, Verna McErlane, Margaret Murray et al. · Cancer Gene Therapy · 2006 · 40 citations

Medicine, Oncology, Pharmacology +15