Karen A. Brause

Orally Active .beta.-Lactam Inhibitors of Human Leukocyte Elastase. 3. Stereospecific Synthesis and Structure-Activity Relationships for 3,3-Dialkylazetidin-2-ones

P E Finke, S. K. Shah, D. Fletcher et al. · Journal of Medicinal Chemistry · 1995 · 89 citations · Full text

Orally active .beta.-lactam inhibitors of human leukocyte elastase-1. Activity of 3,3-diethyl-2-azetidinones

S. K. Shah, Conrad P. Dorn, P E Finke et al. · Journal of Medicinal Chemistry · 1992 · 68 citations

Inhibition of human leukocyte elastase. 4. Selection of a substituted cephalosporin (L-658,758) as a topical aerosol

Paul E. Finke, Shrenik K. Shah, Bonnie M. Ashe et al. · Journal of Medicinal Chemistry · 1992 · 53 citations · Full text

Pharmaceutical Science, Bioorganic Chemistry, Human Leukocyte Elastase +22

Inhibition of human leukocyte elastase. 3. Synthesis and activity of 3'-substituted cephalosporins

S. K. Shah, Karen A. Brause, Gilbert O. Chandler et al. · Journal of Medicinal Chemistry · 1990 · 48 citations · Full text

Cephalosporin Sulfones, Hle Inhibitory Activity, Medicinal Chemistry +12

Chemical, biochemical, pharmacokinetic, and biological properties of L-680,833: a potent, orally active monocyclic beta-lactam inhibitor of human polymorphonuclear leukocyte elastase.

James B. Doherty, S. K. Shah, Paul E. Finke et al. · Proceedings of the National Academy of Sciences · 1993 · 34 citations · Full text

Pharmaceutical Science, Immunology, Biological Properties +17