Miguel Manzanares

Obesity-associated variants within FTO form long-range functional connections with IRX3

Scott Smemo, Juan J. Tena, Kyoung-Han Kim et al. · Nature · 2014 · 1.3K citations · Full text

Obesity, Metabolic Syndrome, Energy Homeostasis +12

Reprogramming in vivo produces teratomas and iPS cells with totipotency features

María Abad, Lluc Mosteiro, Cristina Pantoja et al. · Nature · 2013 · 535 citations

Totipotency Features, Induced Pluripotent Stem Cell, Developmental Biology +7

An atlas of alternative splicing profiles and functional associations reveals new regulatory programs and genes that simultaneously express multiple major isoforms

Javier Tapial, Kevin Ha, Timothy Sterne-Weiler et al. · Genome Research · 2017 · 477 citations · Full text

Active DNA demethylation at enhancers during the vertebrate phylotypic period

Ozren Bogdanović, Arne H. Smits, Elisa de la Calle‐Mustienes et al. · Nature Genetics · 2016 · 266 citations · Full text

Chromatin, Chromatin Remodeling, Natural Sciences +10

Notch and Hippo Converge on Cdx2 to Specify the Trophectoderm Lineage in the Mouse Blastocyst

Teresa Rayón, Sergio Menchero, Andrés Nieto et al. · Developmental Cell · 2014 · 240 citations · Full text

Biology, Knockout Mouse, Lineage Plasticity +11