Arek Kendirli

Gene Essentiality Profiling Reveals Gene Networks and Synthetic Lethal Interactions with Oncogenic Ras

Haiyan Yu, Nicholas W. Hughes, Bingxu Liu et al. · Cell · 2017 · 664 citations · Full text

Functional Genomics, Oncogenic Ras, Synthetic Lethal Interactions +10

Mononuclear phagocytes locally specify and adapt their phenotype in a multiple sclerosis model

Giuseppe Locatelli, Delphine Theodorou, Arek Kendirli et al. · Nature Neuroscience · 2018 · 142 citations

Inflammation, Autoimmune Disease, Adaptive Immune System +13

Targeting the TCA cycle can ameliorate widespread axonal energy deficiency in neuroinflammatory lesions

Yi-Heng Tai, Daniel Engels, Giuseppe Locatelli et al. · Nature Metabolism · 2023 · 62 citations · Full text

Mitochondrial Oxidation, Social Sciences, Oxidative Stress +20

A genome-wide in vivo CRISPR screen identifies essential regulators of T cell migration to the CNS in a multiple sclerosis model

Arek Kendirli, Clara de la Rosa, Katrin F. Lämmle et al. · Nature Neuroscience · 2023 · 32 citations · Full text

RORγt-expressing dendritic cells are functionally versatile and evolutionarily conserved antigen-presenting cells

Hamsa Narasimhan, Maria Lucia Richter, Ramin Shakiba et al. · Proceedings of the National Academy of Sciences · 2025 · 31 citations · Full text