Paul Rose

Structural analysis of the lymphocyte-specific kinase Lck in complex with non-selective and Src family selective kinase inhibitors

Xiaotian Zhu, Joseph L. Kim, John Newcomb et al. · Structure · 1999 · 255 citations · Full text

Signal Transduction, Receptor Tyrosine Kinase, Molecular Biology +8

Mutation in the Jak Kinase JH2 Domain Hyperactivates <i>Drosophila</i> and Mammalian Jak-Stat Pathways

Hong Luo, Paul Rose, Dwayne L. Barber et al. · Molecular and Cellular Biology · 1997 · 244 citations · Full text

Design, Synthesis, and Evaluation of Orally Active Benzimidazoles and Benzoxazoles as Vascular Endothelial Growth Factor-2 Receptor Tyrosine Kinase Inhibitors

Michele Potashman, James Bready, Angela Coxon et al. · Journal of Medicinal Chemistry · 2007 · 166 citations · Full text

Crystal Structure of an Inactive Akt2 Kinase Domain

Xin Huang, Michael J. Begley, Kurt Morgenstern et al. · Structure · 2003 · 138 citations

Crystal Structure, Signal Transduction, Molecular Physiology +7

c-Met Inhibitors with Novel Binding Mode Show Activity against Several Hereditary Papillary Renal Cell Carcinoma-related Mutations

Steven F. Bellon, Paula Kaplan‐Lefko, Yajing Yang et al. · Journal of Biological Chemistry · 2007 · 137 citations · Full text