M. NAGASAWA

Synthetic Studies of Halichondrin B, an Antitumor Polyether Macrolide Isolated from a Marine Sponge. 3. Synthesis of C27-C36 Subunit<i>via</i>Completely Stereoselective<i>C</i>-Glycosylation to the F Ring

K. HORITA, Y. SAKURAI, M. NAGASAWA et al. · Synlett · 1994 · 41 citations

Natural Sciences, Chemistry, Medicinal Chemistry +15

Synthetic Studies of Halichondrin B, an Antitumor Polyether Macrolide Isolated from a Marine Sponge. 1. Stereoselective Synthesis of the C1-C13 Fragment<i>via</i>Construction of the B and A Rings by Kinetically and thermodynamically Controlled Intramolecular Michael Reactions.

K. HORITA, S. Hachiya, M. NAGASAWA et al. · Synlett · 1994 · 34 citations

Natural Sciences, Chemistry, Medicinal Chemistry +15

Synthetic Studies of Halichondrin B, an Antitumor Polyether Macrolide Isolated from a Marine Sponge. 7. Synthesis of Two C27-C36 Units via Construction of the F Ring and Completely Stereoselective C-Glycosylation Using Mixed Lewis Acids.

Kiyoshi Horita, Youji SAKURAI, M. NAGASAWA et al. · Chemical and Pharmaceutical Bulletin · 1997 · 21 citations · Full text

Pharmacy, Chemistry, Medicinal Chemistry +13

Synthetic Studies of Halichondrin B, an Antitumor Polyether Macrolide Isolated from a Marine Sponge 5. A Highly Concise and Efficient Synthesis of the C37~C54 Tricyclic JKL-Ring Part

Kiyoshi Horita, S. Hachiya, Kazuhito Ogihara et al. · Heterocycles · 1996 · 20 citations · Full text

Natural Sciences, Chemistry, Medicinal Chemistry +15

Synthetic studies of halichondrin B, an antitumor polyether macrolide isolated from a marine sponge. 8. Synthesis of the lactone part (C1C36) via horner-emmons coupling between C1C15 and C16C36 fragments and Yamaguchi lactonization

Kiyoshi Horita, M. NAGASAWA, S. Hachiya et al. · Tetrahedron Letters · 1997 · 19 citations

Natural Sciences, Chemistry, Medicinal Chemistry +17