Kirk Wright

Allosteric Mutant IDH1 Inhibitors Reveal Mechanisms for IDH1 Mutant and Isoform Selectivity

Xiaoling Xie, Daniel Baird, Kimberly Elizabeth Bowen et al. · Structure · 2017 · 66 citations

Pharmacy, Medicinal Chemistry, Molecular Biology +14

Toward the Validation of Maternal Embryonic Leucine Zipper Kinase: Discovery, Optimization of Highly Potent and Selective Inhibitors, and Preliminary Biology Insight

B. Barry Touré, J. Giraldes, Troy Smith et al. · Journal of Medicinal Chemistry · 2016 · 52 citations · Full text

Medicine, Oncology, Pharmacology +16

Embryonic disruption of the candidate dyslexia susceptibility gene homolog Kiaa0319-like results in neuronal migration disorders

Maryann P. Platt, William T. Adler, Alison J. Mehlhorn et al. · Neuroscience · 2013 · 36 citations

Life Sciences, Genetics, Neuroscience +16

The structure of the BIR3 domain of cIAP1 in complex with the N-terminal peptides of SMAC and caspase-9

Raviraj Kulathila, Brian Vash, David R. Sage et al. · Acta Crystallographica Section D Biological Crystallography · 2008 · 34 citations

Life Sciences, Biochemistry, Molecular Biology +14