Jonathan W. Kotula

Engineered bacteria can function in the mammalian gut long-term as live diagnostics of inflammation

David T. Riglar, Tobias W. Giessen, Michael Baym et al. · Nature Biotechnology · 2017 · 423 citations · Full text

Life Sciences, Immunology, Microbiology +14

An engineered <i>E. coli</i> Nissle improves hyperammonemia and survival in mice and shows dose-dependent exposure in healthy humans

Caroline Kurtz, Yves Millet, Marja Puurunen et al. · Science Translational Medicine · 2019 · 392 citations

Life Sciences, Biological Engineering, Biotechnology +12

Programmable bacteria detect and record an environmental signal in the mammalian gut

Jonathan W. Kotula, S. Jordan Kerns, Lev Shaket et al. · Proceedings of the National Academy of Sciences · 2014 · 369 citations · Full text

Life Sciences, Bioengineering, Microbiology +15

Aptamer-Mediated Delivery of Splice-Switching Oligonucleotides to the Nuclei of Cancer Cells

Jonathan W. Kotula, Elizabeth D. Pratico, Xin Ming et al. · Nucleic Acid Therapeutics · 2012 · 118 citations · Full text

Pharmacy, Molecular Biology, Oncology +14

A distributed cell division counter reveals growth dynamics in the gut microbiota

Cameron Myhrvold, Jonathan W. Kotula, Wade M. Hicks et al. · Nature Communications · 2015 · 59 citations · Full text

Life Sciences, Biology, Microbiology +17