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Paul Blakeley, Norah M. E. Fogarty, Ignacio del Valle, +7

Development

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Jennifer R. Gruhn, Agata P. Zielinska, Vallari Shukla, +27

Science

Chromosome ErrorsFertilityGeneticsReproductive HealthGynecology +16

Genome editing reveals a role for OCT4 in human embryogenesis

Norah M. E. Fogarty, Afshan McCarthy, Kirsten E Snijders, +15

Nature

Developmental BiologyGeneticsMorphogenesisGene EditingHuman Embryonic Development +8

Error-prone chromosome-mediated spindle assembly favors chromosome segregation defects in human oocytes

Zuzana Holubcová, Martyn Blayney, Kay Elder, +1

Science

OocyteFertilityGeneticsMolecular BiologyHuman Eggs +19

Initiation of a conserved trophectoderm program in human, cow and mouse embryos

Claudia Gerri, Afshan McCarthy, Gregorio Alanis‐Lobato, +12

Nature

BiologyEmbryonic Stem CellAnimal ReproductionDevelopmental BiologyMouse Embryos +8

Human hypoblast formation is not dependent on FGF signalling

Mila Roode, Kathryn Blair, Philip Snell, +4

Developmental Biology

Signal TransductionDevelopmental BiologyTissue DevelopmentHuman Hypoblast FormationPreimplantation Development +11

Parental genome unification is highly error-prone in mammalian embryos

Tommaso Cavazza, Yuko Takeda, Antonio Z. Politi, +12

Cell

Mammalian oocytes store mRNAs in a mitochondria-associated membraneless compartment

Shiya Cheng, Gerrit Altmeppen, Chun So, +11

Science

OocyteFull-grown OocytesDevelopmental BiologyMitochondrial BiogenesisMitochondrial Function +12

Sister kinetochore splitting and precocious disintegration of bivalents could explain the maternal age effect

Agata P. Zielinska, Zuzana Holubcová, Martyn Blayney, +2

eLife

Mechanism of spindle pole organization and instability in human oocytes

Chun So, Katerina Menelaou, Julia Uraji, +13

Science